| $150,000–350,000 | ABF DENTAL PL | ORANGE CITY, FL | Itria Ventures LLC |
| $150,000–350,000 | ABF DENTAL, PL | ORANGE CITY, FL | Ameris Bank |
| $150,000–350,000 | ADVANCED IMAGING PARTNERS, LLC | ORANGE CITY, FL | Synovus Bank |
| $150,000–350,000 | ALL LEADERS PRE-SCHOOL CORP | ORANGE CITY, FL | American Momentum Bank |
| $350,000–1 million | ALL TERRAIN TRACTOR SERVICE, INC. | ORANGE CITY, FL | Fairwinds CU |
| $350,000–1 million | ATLANTIC EAR NOSE & THROAT PA | ORANGE CITY, FL | Truist Bank |
| $150,000–350,000 | C & S TOWING SERVICE INC | ORANGE CITY, FL | Mainstreet Community Bank of Florida |
| $150,000–350,000 | CATALOG SOLUTIONS, INC., | ORANGE CITY, FL | United Community Bank |
| $150,000–350,000 | CENTRAL FLORIDA BONE AND JOINT INSTITUTE, PLLC | ORANGE CITY, FL | JPMorgan Chase Bank, National Association |
| $150,000–350,000 | CENTRAL FLORIDA LIFTSTATIONS, INC. | ORANGE CITY, FL | TD Bank, National Association |
| $350,000–1 million | CHINCHOR ELECTRIC INC | ORANGE CITY, FL | Mainstreet Community Bank of Florida |
| $150,000–350,000 | CJR CONCRETE INC | ORANGE CITY, FL | Bank of America, National Association |
| $150,000–350,000 | CJS COMMUNICATIONS | ORANGE CITY, FL | Mainstreet Community Bank of Florida |
| $150,000–350,000 | ED SENEZ ALUMINUM SPECIALIST INC | ORANGE CITY, FL | Mainstreet Community Bank of Florida |
| $150,000–350,000 | ESQUIRE TITLE SERVICES, INC. | ORANGE CITY, FL | Seacoast National Bank |
| $350,000–1 million | FAMILY MATTERS LLC | ORANGE CITY, FL | Bremer Bank, National Association |
| $150,000–350,000 | FIRST BAPTIST CHURCH HOLDING COMPANY OF ORANGE CITY FLORIDA, | ORANGE CITY, FL | Cogent Bank |
| $2–5 million | FIRST QUALITY PLUMBING AND IRRIGATION, INC | ORANGE CITY, FL | Mainstreet Community Bank of Florida |
| $150,000–350,000 | FLORIDA KIDNEY AND HYPERTENSION SPECIALISTS, PA | ORANGE CITY, FL | Regions Bank |
| $350,000–1 million | GEL LLC | ORANGE CITY, FL | Synovus Bank |
| $350,000–1 million | HARTY TRACTOR SERVICES INC | ORANGE CITY, FL | Mainstreet Community Bank of Florida |
| $350,000–1 million | HOWARD J. SAKOWITZ, MD, PA | ORANGE CITY, FL | Truist Bank |
| $150,000–350,000 | JAMES RAYNOR INSURANCE AGENCY, INC | ORANGE CITY, FL | TD Bank, National Association |
| $150,000–350,000 | JENA MEDICAL GROUP, LLC | ORANGE CITY, FL | Cross River Bank |
| $150,000–350,000 | JL STONE CONSTRUCTION, LLC | ORANGE CITY, FL | Fairwinds CU |
| $150,000–350,000 | JM SPRAY INC. | ORANGE CITY, FL | Fifth Third Bank |
| $150,000–350,000 | KLEIN CORPORATION INC | ORANGE CITY, FL | Seacoast National Bank |
| $150,000–350,000 | LELO'S ENTERPRISES CORPORATION | ORANGE CITY, FL | Bank of America, National Association |
| $350,000–1 million | MECHANICAL INSULATION & TECHNOLOGIES, LLC | ORANGE CITY, FL | Truist Bank |
| $350,000–1 million | METRIX LLC | ORANGE CITY, FL | The Citizens National Bank of Meridian |
| $2–5 million | MID-FLORIDA HEMATOLOGY AND ONCOLOGY CENTERS PA | ORANGE CITY, FL | Regions Bank |
| $150,000–350,000 | NINE SQUARE ROOFING AND CONSTRUCTION, LLC | ORANGE CITY, FL | JPMorgan Chase Bank, National Association |
| $150,000–350,000 | NORTH ORLANDO SURGICAL GROUP INC | ORANGE CITY, FL | Seacoast National Bank |
| $150,000–350,000 | ORANGE CITY SURGICAL, LLC | ORANGE CITY, FL | Mainstreet Community Bank of Florida |
| $150,000–350,000 | PULMONARY PRACTICE ASSOC | ORANGE CITY, FL | Truist Bank |
| $150,000–350,000 | SANDCASTLE CARE II, LLC | ORANGE CITY, FL | Seacoast National Bank |
| $1–2 million | SUPERIOR SHEDS INC | ORANGE CITY, FL | Bank of America, National Association |