| $350,000–1 million | PAO BRASIL BAKERY INC. | FRAMINGHAM, MA | Eastern Bank |
| $150,000–350,000 | PARSONS COMMERCIAL GROUP INC | FRAMINGHAM, MA | Middlesex Savings Bank |
| $150,000–350,000 | PAUL FLAHERTY PLUMBING & HEATING COMPANY, INC. | FRAMINGHAM, MA | Middlesex Savings Bank |
| $150,000–350,000 | PAUL'S RESAURANT, INC. | FRAMINGHAM, MA | MutualOne Bank |
| $150,000–350,000 | PEARTREE CORPORATION | FRAMINGHAM, MA | Middlesex Savings Bank |
| $350,000–1 million | PEERLESS MEDIA, LLC | FRAMINGHAM, MA | Valley National Bank |
| $150,000–350,000 | PESTEX INC | FRAMINGHAM, MA | Eastern Bank |
| $5–10 million | PR RESTAURANTS L.L.C. | FRAMINGHAM, MA | Needham Bank |
| $350,000–1 million | PRECISION FITNESS EQUIPMENT, INC. | FRAMINGHAM, MA | TD Bank, National Association |
| $150,000–350,000 | RANGER ENGINEERING, INC. | FRAMINGHAM, MA | Middlesex Savings Bank |
| $350,000–1 million | RELIABLE ROOFING & SHEET METAL LLC | FRAMINGHAM, MA | Northern Bank and Trust Company |
| $150,000–350,000 | ROGERS INSULATION SPECIALISTS CO., INC. | FRAMINGHAM, MA | MutualOne Bank |
| $150,000–350,000 | SAINT BRIDGET SCHOOL | FRAMINGHAM, MA | Eastern Bank |
| $2–5 million | SAINT PATRICK'S MANOR, INC. | FRAMINGHAM, MA | KeyBank National Association |
| $150,000–350,000 | SALON DESIGNS, INC. | FRAMINGHAM, MA | Berkshire Bank |
| $150,000–350,000 | SAMIOTES CONSULTANTS INC | FRAMINGHAM, MA | Bank of America, National Association |
| $150,000–350,000 | SCHEDULING SYSTEMS INC | FRAMINGHAM, MA | Bank of America, National Association |
| $150,000–350,000 | SHAM, TANG AND TAM P.C. | FRAMINGHAM, MA | Middlesex Savings Bank |
| $150,000–350,000 | SLADE VETERINARY HOSPITAL, INC. | FRAMINGHAM, MA | MutualOne Bank |
| $150,000–350,000 | SMART COATS INC | FRAMINGHAM, MA | Bank of America, National Association |
| $150,000–350,000 | SOLACE THERAPEUTICS INC | FRAMINGHAM, MA | Silicon Valley Bridge Bank NA |
| $350,000–1 million | SOUTHERN NEW ENGLAND CONFERENCE OF THE UNITED CHURCH OF CHRI | FRAMINGHAM, MA | Webster Bank National Association |
| $150,000–350,000 | SUDBURY SENIOR PLACEMENT, INC. | FRAMINGHAM, MA | Webster Five Cents Savings Bank |
| $150,000–350,000 | SUDBURY VALLEY SCHOOL, INC. | FRAMINGHAM, MA | Northern Bank and Trust Company |
| $150,000–350,000 | SUSTAINABLE ENERGY ADVANTAGE, LLC | FRAMINGHAM, MA | Eastern Bank |
| $2–5 million | THE LEARNING CENTER FOR THE DEAF INC | FRAMINGHAM, MA | TD Bank, National Association |
| $2–5 million | THE PORTLAND GROUP, INC. | FRAMINGHAM, MA | Manufacturers and Traders Trust Company |
| $150,000–350,000 | THE SPEECH IMPROVEMENT COMPANY INC | FRAMINGHAM, MA | St. Mary's CU |
| $150,000–350,000 | THE SUMMIT MONTESSORI SCHOOL | FRAMINGHAM, MA | MutualOne Bank |
| $150,000–350,000 | THE SUPPORT GROUP, INC. | FRAMINGHAM, MA | Middlesex Savings Bank |
| $150,000–350,000 | THE TEDDY BEAR VILLAGE INC. | FRAMINGHAM, MA | Avidia Bank |
| $350,000–1 million | TOMMY'S TAXI, INC. | FRAMINGHAM, MA | MutualOne Bank |
| $150,000–350,000 | TOSTI'S SERVICE CENTER | FRAMINGHAM, MA | Middlesex Savings Bank |
| $150,000–350,000 | UNIQUE DENTAL OF FRAMINGHAM LLC | FRAMINGHAM, MA | Avidia Bank |
| $150,000–350,000 | UNITED SALVAGE CORP. OF AMERICA | FRAMINGHAM, MA | MutualOne Bank |
| $350,000–1 million | UNITED WAY OF TRI COUNTRY INC. | FRAMINGHAM, MA | MutualOne Bank |
| $350,000–1 million | VARIANTYX INC. | FRAMINGHAM, MA | Bank of America, National Association |
| $350,000–1 million | VINEYARD ROAD INC | FRAMINGHAM, MA | Middlesex Savings Bank |
| $350,000–1 million | VTT MANAGEMENT INC | FRAMINGHAM, MA | Digital FCU |
| $2–5 million | WAYSIDE YOUTH & FAMILY SUPPORT NETWORK, INC. | FRAMINGHAM, MA | Middlesex Savings Bank |
| $350,000–1 million | WE DO CARE INC. | FRAMINGHAM, MA | MutualOne Bank |
| $150,000–350,000 | WEC HEALTH LLC | FRAMINGHAM, MA | OneLocal Bank |
| $150,000–350,000 | WELLESLEY TRUCKING SERVICE, INC. | FRAMINGHAM, MA | UniBank for Savings |
| $150,000–350,000 | WELLNESS PARTNERS LLC | FRAMINGHAM, MA | Newtek Small Business Finance, Inc. |
| $150,000–350,000 | WORLD-LINK COMMUNICATIONS INC | FRAMINGHAM, MA | Bank of America, National Association |