| $2–5 million | UNITED WAY OF GREATER ST. LOUIS, INC. | SAINT LOUIS, MO | Commerce Bank |
| $350,000–1 million | UNIVERSAL SEWING SUPPLY, INC. | SAINT LOUIS, MO | Cadence Bank |
| $150,000–350,000 | UNIVERSITY DENTAL CARE LLC | SAINT LOUIS, MO | First Mid Bank & Trust, National Association |
| $150,000–350,000 | UNIVERSITY INTERNAL MEDICINE AND DIABET | SAINT LOUIS, MO | U.S. Bank, National Association |
| $350,000–1 million | UNLEASHING POTENTIAL | SAINT LOUIS, MO | Busey Bank |
| $150,000–350,000 | UNLIMITED SERVICES IN TRANSPORTATION, INC | SAINT LOUIS, MO | Bank of Springfield |
| $150,000–350,000 | UPBRAND COLLABORATIVE, LLC | SAINT LOUIS, MO | Enterprise Bank & Trust |
| $350,000–1 million | UPC ENTERPRISES LC | SAINT LOUIS, MO | Midwest Regional Bank |
| $350,000–1 million | URBAN CHESTNUT BREWING COMPANY, INC. | SAINT LOUIS, MO | Carrollton Bank |
| $350,000–1 million | URBAN IMPROVEMENT CONGLOMERATE, LLC | SAINT LOUIS, MO | Peoples National Bank, National Association |
| $1–2 million | URBAN LEAGUE OF METROPOLITAN ST LOUIS | SAINT LOUIS, MO | Bank of America, National Association |
| $150,000–350,000 | URBAN SPROUTS | SAINT LOUIS, MO | Southern Bank |
| $1–2 million | URBAN STRATEGIES, INC | SAINT LOUIS, MO | Enterprise Bank & Trust |
| $350,000–1 million | URSULINE ACADEMY, KIRKWOOD, MISSOURI | SAINT LOUIS, MO | Enterprise Bank & Trust |
| $350,000–1 million | US BAND & ORCHESTRA SUPPLIES, INC. | SAINT LOUIS, MO | Midwest Regional Bank |
| $350,000–1 million | US POLYMERS - ACCUREZ, LLC | SAINT LOUIS, MO | Commerce Bank |
| $350,000–1 million | USH AQUARIUM LLC | SAINT LOUIS, MO | Bank of Washington |
| $2–5 million | USH MASTER TENANT LLC | SAINT LOUIS, MO | Bank of Washington |
| $150,000–350,000 | USH WHEEL LLC | SAINT LOUIS, MO | Bank of Washington |
| $150,000–350,000 | V THREE STUDIOS LLC | SAINT LOUIS, MO | Commerce Bank |
| $350,000–1 million | VAC-IT-ALL SERVICES INC. | SAINT LOUIS, MO | U.S. Bank, National Association |
| $150,000–350,000 | VACCARO AND SONS PRODUCE, INC | SAINT LOUIS, MO | Carrollton Bank |
| $150,000–350,000 | VADIM BARAM INC. | SAINT LOUIS, MO | St. Louis Bank |
| $150,000–350,000 | VALTEC HYDRAULICS, INC. | SAINT LOUIS, MO | Midwest BankCentre |
| $150,000–350,000 | VANDEVENTER MACHINE WORKS CORP. | SAINT LOUIS, MO | The Central Trust Bank |
| $150,000–350,000 | VANIT DELIVERY LLC | SAINT LOUIS, MO | PNC Bank, National Association |
| $350,000–1 million | VANTAGELINKS, LLC | SAINT LOUIS, MO | Simmons Bank |
| $150,000–350,000 | VCL ENTERPRISES INC | SAINT LOUIS, MO | U.S. Bank, National Association |
| $5–10 million | VEE-JAY CEMENT CONTRACTING CO., INC. | SAINT LOUIS, MO | UMB Bank, National Association |
| $350,000–1 million | VEGA TRANSPORT LLC | SAINT LOUIS, MO | Midwest BankCentre |
| $150,000–350,000 | VELOCIDATA, INC. | SAINT LOUIS, MO | Banc of California |
| $1–2 million | VERNON L GOEDECKE COMPANY INC | SAINT LOUIS, MO | West Community CU |
| $150,000–350,000 | VESSEL ARCHITECTURE AND DESIGN INC. | SAINT LOUIS, MO | Triad Bank |
| $1–2 million | VESTAL CORPORATION | SAINT LOUIS, MO | The Central Trust Bank |
| $150,000–350,000 | VESTECH SECURITIES, INC. | SAINT LOUIS, MO | U.S. Bank, National Association |
| $350,000–1 million | VETA, LLC | SAINT LOUIS, MO | Midwest BankCentre |
| $1–2 million | VETERANS HOME CARE LLC | SAINT LOUIS, MO | Busey Bank |
| $150,000–350,000 | VHSDPS RESTAURANTS LLC | SAINT LOUIS, MO | PNC Bank, National Association |
| $350,000–1 million | VICON CONSTRUCTION LLC | SAINT LOUIS, MO | Busey Bank |
| $150,000–350,000 | VICTORY STEEL PRODUCTS CORPORATION | SAINT LOUIS, MO | BMO Bank National Association |
| $150,000–350,000 | VILLA DI MARIA MONTESSORI SCHOOL | SAINT LOUIS, MO | Simmons Bank |
| $1–2 million | VILLA DUCHESNE AND OAK HILL SCHOOL | SAINT LOUIS, MO | Commerce Bank |
| $1–2 million | VILLA LIGHTING SUPPLY, INC. | SAINT LOUIS, MO | The Central Trust Bank |
| $150,000–350,000 | VINCE GRAYE SLATE & TILE ROOFING CO | SAINT LOUIS, MO | The First National Bank of Waterloo |
| $2–5 million | VINTECH SOLUTIONS, INC. | SAINT LOUIS, MO | SSB Bank |
| $1–2 million | VIP DISTRIBUTING COMPANY | SAINT LOUIS, MO | Simmons Bank |
| $150,000–350,000 | VISION CARE CONSULTANTS, INC. | SAINT LOUIS, MO | Midwest BankCentre |
| $150,000–350,000 | VISION CARE PARTNERS, LLC | SAINT LOUIS, MO | Great Southern Bank |
| $150,000–350,000 | VISITING NURSE ASSOCIATION OF GREATER ST. LOUIS | SAINT LOUIS, MO | Justine Petersen Housing & Reinvestment Corporation |
| $150,000–350,000 | VITAL HOME CARE SERVICES LLC | SAINT LOUIS, MO | U.S. Bank, National Association |
| $5–10 million | VITALIGENT, LLC | SAINT LOUIS, MO | Lake Forest Bank & Trust Company, National Association |
| $350,000–1 million | VITRO PRODUCTS,INC. | SAINT LOUIS, MO | Montgomery Bank |
| $150,000–350,000 | VOBIS SANUS, LLC | SAINT LOUIS, MO | The Central Trust Bank |
| $2–5 million | VOLPI FOODS INC | SAINT LOUIS, MO | Arvest Bank |
| $150,000–350,000 | VUCO INC | SAINT LOUIS, MO | Midwest BankCentre |
| $350,000–1 million | W C & D ENTERPRISES, INC | SAINT LOUIS, MO | Midwest BankCentre |
| $150,000–350,000 | W D QUINN SAW COMPANY | SAINT LOUIS, MO | St. Johns Bank and Trust Company |
| $350,000–1 million | W. SCHILLER & CO., INC. | SAINT LOUIS, MO | Cass Commercial Bank |
| $350,000–1 million | WALLACH IRON & METAL CO INC | SAINT LOUIS, MO | Cass Commercial Bank |
| $150,000–350,000 | WALTER WURDACK INC. | SAINT LOUIS, MO | Midwest Regional Bank |
| $150,000–350,000 | WARNER COMMUNICATIONS | SAINT LOUIS, MO | Bank of America, National Association |
| $150,000–350,000 | WARNING LITES OF ST LOUIS INC | SAINT LOUIS, MO | PNC Bank, National Association |
| $1–2 million | WARSON GROUP, INC. | SAINT LOUIS, MO | Commerce Bank |
| $350,000–1 million | WASABI MANAGEMENT CO INC | SAINT LOUIS, MO | Peoples National Bank, National Association |
| $350,000–1 million | WASTE CONTROLLERS, INC. | SAINT LOUIS, MO | Busey Bank |
| $2–5 million | WATERHOUT CONSTRUCTION COMPANY INC | SAINT LOUIS, MO | Simmons Bank |
| $150,000–350,000 | WATSON COATINGS, INC. | SAINT LOUIS, MO | Simmons Bank |
| $150,000–350,000 | WATSON LABEL PRODUCTS | SAINT LOUIS, MO | Cass Commercial Bank |
| $150,000–350,000 | WATSON ROAD VETERINARY CLINIC | SAINT LOUIS, MO | Midwest BankCentre |
| $350,000–1 million | WAYNE AUTOMATIC SPRINKLER CORP | SAINT LOUIS, MO | UMB Bank, National Association |
| $150,000–350,000 | WEBB ENGINEERING SERVICES, INC. | SAINT LOUIS, MO | First Financial Bank, National Association |
| $2–5 million | WEBER CHEVROLET COMPANY | SAINT LOUIS, MO | Bank of Washington |
| $150,000–350,000 | WEBER FIRE AND SAFETY EQUIPMENT CO. | SAINT LOUIS, MO | Enterprise Bank & Trust |
| $350,000–1 million | WEBER INDUSTRIES, INC | SAINT LOUIS, MO | Carrollton Bank |
| $150,000–350,000 | WEBSHACKING6, LLC | SAINT LOUIS, MO | American Bank of Freedom |
| $150,000–350,000 | WEBSTER CHILD CARE CENTER AT LACLEDE GROVES | SAINT LOUIS, MO | Midwest BankCentre |
| $150,000–350,000 | WEBSTER DENTAL CARE, INC | SAINT LOUIS, MO | First Bank |
| $350,000–1 million | WEBSTER GROVES ANIMAL HOSPITAL PC | SAINT LOUIS, MO | Commerce Bank |
| $350,000–1 million | WEDGEWOOD PARTNERS | SAINT LOUIS, MO | U.S. Bank, National Association |
| $150,000–350,000 | WEINHARDT PARTY RENTALS, INC | SAINT LOUIS, MO | Midwest BankCentre |
| $350,000–1 million | WEINTZ CLEANING INC | SAINT LOUIS, MO | PNC Bank, National Association |
| $2–5 million | WEISSMAN'S THEATRICAL SUPPLIES, INC. | SAINT LOUIS, MO | First Bank |
| $350,000–1 million | WELLINGTON ENVIRONMENTAL CONSULTING & CONSTRUCTION INC | SAINT LOUIS, MO | Simmons Bank |
| $1–2 million | WELSCH FURNACE COMPANY, INC. | SAINT LOUIS, MO | Midwest BankCentre |
| $150,000–350,000 | WEST CONSULTANT LLC | SAINT LOUIS, MO | PNC Bank, National Association |
| $150,000–350,000 | WEST COUNTY AUTO BODY REPAIR, INC. | SAINT LOUIS, MO | U.S. Bank, National Association |
| $150,000–350,000 | WEST COUNTY CARDIOTHORACIC ANESTHESIA IN | SAINT LOUIS, MO | Bank of America, National Association |
| $2–5 million | WEST COUNTY RADIOLOGICAL GROUP INC | SAINT LOUIS, MO | Bank of America, National Association |
| $350,000–1 million | WEST LLC | SAINT LOUIS, MO | Bank of Washington |
| $350,000–1 million | WESTEND CLINIC INC | SAINT LOUIS, MO | Southern Bank |
| $150,000–350,000 | WESTERN BLOW PIPE, INC. | SAINT LOUIS, MO | New Era Bank |
| $2–5 million | WESTERN DIESEL SERVICES INC | SAINT LOUIS, MO | Enterprise Bank & Trust |
| $150,000–350,000 | WESTIN TRADING, INC. | SAINT LOUIS, MO | First Bank |
| $1–2 million | WESTPORT INVESTMENT GROUP LLC | SAINT LOUIS, MO | Bank of Washington |
| $150,000–350,000 | WESTPORT PERIODONTICS | SAINT LOUIS, MO | Montgomery Bank |
| $350,000–1 million | WHEELHOUSE 20 LLC | SAINT LOUIS, MO | Bank of America, National Association |
| $150,000–350,000 | WHITE FLAG CHRISTIAN CHURCH | SAINT LOUIS, MO | Southern Bank |
| $150,000–350,000 | WHITE HOUSE RETREAT, INC | SAINT LOUIS, MO | Lindell Bank & Trust Company |
| $150,000–350,000 | WHITE PEAK INVESTMENTS, LLC | SAINT LOUIS, MO | Midland States Bank |
| $1–2 million | WHITFIELD SCHOOL, INC | SAINT LOUIS, MO | Carrollton Bank |