| $150,000–350,000 | SHEEHAN'S PHARMACY, INC | WILKES BARRE, PA | Landmark Community Bank |
| $150,000–350,000 | SHIRSON ENTERPRISES, INC. | WILKES BARRE, PA | FNCB Bank |
| $350,000–1 million | SMART ENTERPRISES, INC | WILKES BARRE, PA | Readycap Lending, LLC |
| $350,000–1 million | SMOKIN JOES TOBACCO SHOP INC | WILKES BARRE, PA | Wells Fargo Bank, National Association |
| $150,000–350,000 | SNL TRUCKING LLC | WILKES BARRE, PA | Peoples Security Bank and Trust Company |
| $150,000–350,000 | ST. NICK ST. MARY ELEMENTARY SCHOOL OF DIOCESE OF SCRANTON | WILKES BARRE, PA | FNCB Bank |
| $350,000–1 million | STEFFIE ENTERPRISES, INC. | WILKES BARRE, PA | FNCB Bank |
| $350,000–1 million | STELL ENTERPRISES INC. | WILKES BARRE, PA | Landmark Community Bank |
| $350,000–1 million | SUN RUSTIC LLC | WILKES BARRE, PA | Wells Fargo Bank, National Association |
| $2–5 million | SUNDANCE VACATIONS, INC. | WILKES BARRE, PA | Community Bank, National Association |
| $150,000–350,000 | SVP WEST LLC | WILKES BARRE, PA | TD Bank, National Association |
| $350,000–1 million | TAMMAC HOLDINGS CORPORATION | WILKES BARRE, PA | FNCB Bank |
| $150,000–350,000 | THE SOCIETY FOR THE PREVENTION OF CRUELTY TO ANIMALS OF LUZERNE COUNTY | WILKES BARRE, PA | Community Bank, National Association |
| $2–5 million | TRION INDUSTRIES INC | WILKES BARRE, PA | PNC Bank, National Association |
| $150,000–350,000 | UNITED MECHANICAL CORPORATION | WILKES BARRE, PA | FNCB Bank |
| $150,000–350,000 | UNITED WAY OF WYOMING VALLEY INC | WILKES BARRE, PA | Community Bank, National Association |
| $350,000–1 million | VALLEY CHEVROLET INC | WILKES BARRE, PA | PNC Bank, National Association |
| $350,000–1 million | VALLEY DISTRIBUTING AND STORAGE CO., INC. | WILKES BARRE, PA | Community Bank, National Association |
| $150,000–350,000 | VPHARM, INC. T/A KEYSTONE PROFESSIONAL PHARMACY | WILKES BARRE, PA | FNCB Bank |
| $150,000–350,000 | WASTE REDUCTION RECYCLING AND TRANSFER INC. | WILKES BARRE, PA | FNCB Bank |
| $150,000–350,000 | WILKES-BARRE ACADEMY INC | WILKES BARRE, PA | Landmark Community Bank |
| $150,000–350,000 | WYOMING VALLEY ALCOHOL AND DRUG SERVICES, INC. | WILKES BARRE, PA | Landmark Community Bank |
| $150,000–350,000 | WYOMING VLY PATHOLOGY ASSOCIATION PC | WILKES BARRE, PA | PNC Bank, National Association |
| $350,000–1 million | YOUNG MENS CHRISTIAN ASSOCIATION OF WILKES-BARRE | WILKES BARRE, PA | Fidelity Deposit and Discount Bank |