| $150,000–350,000 | ACADEMY CENTER OF THE ARTS | LYNCHBURG, VA | First National Bank |
| $150,000–350,000 | ACCUTECH FABRICATION INC | LYNCHBURG, VA | Bank of the James |
| $350,000–1 million | ADVANCED MANUFACTURING TECHNOLOGY INC | LYNCHBURG, VA | First-Citizens Bank & Trust Company |
| $150,000–350,000 | ALH INC. | LYNCHBURG, VA | Select Bank |
| $150,000–350,000 | AMAZEMENT SQUARE, INC. | LYNCHBURG, VA | Truist Bank |
| $1–2 million | AMERICAN HOFMANN CORPORATION | LYNCHBURG, VA | Select Bank |
| $150,000–350,000 | AMG, INC. | LYNCHBURG, VA | Truist Bank |
| $350,000–1 million | ANDERSON CONSTRUCTION, INC. | LYNCHBURG, VA | Select Bank |
| $350,000–1 million | APPLE FORD OF LYNCHBURG INC | LYNCHBURG, VA | Truist Bank |
| $150,000–350,000 | AQUA PROS POOLS & SPAS INC. | LYNCHBURG, VA | Atlantic Union Bank |
| $150,000–350,000 | ARCHITECTURAL PARTNERS | LYNCHBURG, VA | The First Bank and Trust Company |
| $350,000–1 million | ARMES PRECISION MACHINING & FABRICATION INC | LYNCHBURG, VA | Atlantic Union Bank |
| $150,000–350,000 | ATLANTIC CONSTRUCTION SALES, INC. | LYNCHBURG, VA | Select Bank |
| $150,000–350,000 | ATLANTIC PRECISION RESOURCE INC. | LYNCHBURG, VA | Atlantic Union Bank |
| $2–5 million | AUTOMATED CONVEYOR SYSTEMS, INC. | LYNCHBURG, VA | Truist Bank |
| $150,000–350,000 | BAILESS TRUCKING, INC. | LYNCHBURG, VA | First National Bank |
| $150,000–350,000 | BEE LINE TRANSPORT INC | LYNCHBURG, VA | Atlantic Union Bank |
| $350,000–1 million | BENCHMARK SYSTEMS OF W VA INC | LYNCHBURG, VA | Select Bank |
| $350,000–1 million | BERGLUND LUXURY AUTO INC | LYNCHBURG, VA | Atlantic Union Bank |
| $150,000–350,000 | BEST G.C. INC. | LYNCHBURG, VA | The First Bank and Trust Company |
| $350,000–1 million | BLUE RIDGE EAR, NOSE, THROAT & PLASTIC SURGERY, INC. | LYNCHBURG, VA | First-Citizens Bank & Trust Company |
| $150,000–350,000 | BLUE RIDGE THERAPY ASSOCIATES INC. | LYNCHBURG, VA | First-Citizens Bank & Trust Company |
| $150,000–350,000 | BLUE WATER MANAGEMENT LLC | LYNCHBURG, VA | Bank of the James |
| $350,000–1 million | BLUFFWALK CENTER LP | LYNCHBURG, VA | First Bank |
| $350,000–1 million | BMS DIRECT, INC | LYNCHBURG, VA | Bank of the James |
| $350,000–1 million | BOHLING STEEL INC. | LYNCHBURG, VA | Select Bank |
| $150,000–350,000 | BRADY & CRIST DENTISTS INC | LYNCHBURG, VA | Atlantic Union Bank |
| $150,000–350,000 | BROCKMAN, DRINKARD & PENNINGTON, PC | LYNCHBURG, VA | Select Bank |
| $350,000–1 million | BWF AUTOMOTIVE-1 LLC | LYNCHBURG, VA | Atlantic Union Bank |
| $150,000–350,000 | BWF AUTOMOTIVE-2, LLC | LYNCHBURG, VA | Atlantic Union Bank |
| $350,000–1 million | BYRD ENTERPRISES UNLIMITED, INC. | LYNCHBURG, VA | The First Bank and Trust Company |
| $350,000–1 million | CAPPS SHOE COMPANY | LYNCHBURG, VA | Atlantic Union Bank |
| $350,000–1 million | CASKIE & FROST, A PROFESSIONAL CORPORATION | LYNCHBURG, VA | Bank of the James |
| $350,000–1 million | CENTRAL VIRGINIA ALLIANCE FOR COMMUNITY LIVING, INC. | LYNCHBURG, VA | Atlantic Union Bank |
| $150,000–350,000 | CENTRAL VIRGINIA COMMUNICATIONS & MULTIMEDIA INC, | LYNCHBURG, VA | Select Bank |
| $150,000–350,000 | CENTRAL VIRGINIA FAMILY DENTISTRY | LYNCHBURG, VA | Bank of the James |
| $150,000–350,000 | CENTRAL VIRGINIA IMAGING LLC | LYNCHBURG, VA | Bank of the James |
| $150,000–350,000 | CHARLEYS RESTAURANT | LYNCHBURG, VA | Select Bank |
| $150,000–350,000 | CHARTER OF LYNCHBURG, INC. | LYNCHBURG, VA | First National Bank |
| $150,000–350,000 | CHRIS' LAWN CARE, INC. | LYNCHBURG, VA | The First Bank and Trust Company |
| $150,000–350,000 | CLARION AUTOMOTIVE INC. | LYNCHBURG, VA | Select Bank |
| $1–2 million | CLOUDFIT SOFTWARE, LLC | LYNCHBURG, VA | Builtwell Bank |
| $350,000–1 million | COMMUNITY ACCESS NETWORK, INC. | LYNCHBURG, VA | Truist Bank |
| $350,000–1 million | CONSOLIDATED SHOE COMPANY | LYNCHBURG, VA | Truist Bank |
| $350,000–1 million | CONSTRUCTION MANAGEMENT ASSOCIATES, INC | LYNCHBURG, VA | First National Bank |
| $150,000–350,000 | CONSTRUCTION SERVICES INC | LYNCHBURG, VA | Truist Bank |
| $350,000–1 million | COOPER ENTERPRISES INC | LYNCHBURG, VA | Bank of the James |
| $150,000–350,000 | COOPER FAMILY INVESTMENTS, LLC | LYNCHBURG, VA | Bank of the James |
| $150,000–350,000 | COX LAW GROUP, PLLC | LYNCHBURG, VA | Select Bank |
| $350,000–1 million | CRAFT AUTOMOTIVE INC. | LYNCHBURG, VA | Select Bank |
| $350,000–1 million | CRAFT COLLISION CENTER INC. | LYNCHBURG, VA | Select Bank |
| $350,000–1 million | D D & D TRUCKING LLC | LYNCHBURG, VA | Atlantic Union Bank |
| $350,000–1 million | DAVID C. MOORE | LYNCHBURG, VA | Select Bank |
| $350,000–1 million | DAVIDSON, DOYLE & HILTON, LLP | LYNCHBURG, VA | The National Bank of Blacksburg |
| $150,000–350,000 | DAVIS HEATING AND COOLING INC | LYNCHBURG, VA | Truist Bank |
| $5–10 million | DELTA STAR INC. | LYNCHBURG, VA | JPMorgan Chase Bank, National Association |
| $150,000–350,000 | DEPOT LBX, INC. | LYNCHBURG, VA | Bank of the James |
| $350,000–1 million | DERMATOLOGIC AND MOHS SURGERY CONSULTANTS, PLLC | LYNCHBURG, VA | Bank of the James |
| $350,000–1 million | DERMATOLOGY CONSULTANTS, INC. | LYNCHBURG, VA | Pinnacle Bank |
| $150,000–350,000 | ELIZABETH'S EARLY LEARNING CENTER | LYNCHBURG, VA | The First Bank and Trust Company |
| $350,000–1 million | F L MOORE & SONS INC | LYNCHBURG, VA | Select Bank |
| $150,000–350,000 | F. L. SHOWALTER, INCORPORATED | LYNCHBURG, VA | Pinnacle Bank |
| $150,000–350,000 | FALWELL CORPORATION | LYNCHBURG, VA | Carter Bank & Trust |
| $350,000–1 million | FEREBEE JOHNSON COMPANY, INC. | LYNCHBURG, VA | Truist Bank |
| $150,000–350,000 | FIRST CARE HOME HEALTH, INC. | LYNCHBURG, VA | Atlantic Union Bank |
| $150,000–350,000 | FLIPPIN BRUCE & PORTER, INC. | LYNCHBURG, VA | The Farmers Bank of Appomattox |
| $150,000–350,000 | FOREST DENTAL PARTNERS PLLC | LYNCHBURG, VA | TD Bank, National Association |
| $350,000–1 million | FOSTER ELECTRIC COMPANY INC | LYNCHBURG, VA | Truist Bank |
| $150,000–350,000 | FREDERICKSBURG ORTHOPAEDIC ASSOCIATES, PC | LYNCHBURG, VA | Atlantic Union Bank |
| $350,000–1 million | FREEMAN ENTERPRISES INC | LYNCHBURG, VA | Citizens Bank and Trust Company |
| $150,000–350,000 | GARY LOOMIS | LYNCHBURG, VA | Truist Bank |
| $350,000–1 million | GENERATION SOLUTIONS PERSONAL CARE OF LYNCHBURG LLC | LYNCHBURG, VA | Bank of the James |
| $150,000–350,000 | GLASS & ASSOCIATES INC | LYNCHBURG, VA | Bank of the James |
| $350,000–1 million | GOODS CONSTRUCTION COMPANY, INC | LYNCHBURG, VA | Truist Bank |
| $150,000–350,000 | GOSPELINK, INC. | LYNCHBURG, VA | The First Bank and Trust Company |
| $350,000–1 million | HARRIS TIRE COMPANY INC | LYNCHBURG, VA | Atlantic Union Bank |
| $150,000–350,000 | HARVEST LYNCHBURG, LLC | LYNCHBURG, VA | First Bank of the Lake |
| $350,000–1 million | HAWKINS-GRAVES, INC. | LYNCHBURG, VA | Truist Bank |
| $350,000–1 million | HCI-EBS HOLDINS INC | LYNCHBURG, VA | Bank of the James |
| $150,000–350,000 | HIGH PEAK SPORTSWEAR INC | LYNCHBURG, VA | Atlantic Union Bank |
| $150,000–350,000 | HILL CITY MOTORSPORTS INC | LYNCHBURG, VA | Truist Bank |
| $150,000–350,000 | HILL CITY PHARMACY, INC | LYNCHBURG, VA | Bank of the James |
| $1–2 million | HURT & PROFFITT, INCORPORATED | LYNCHBURG, VA | Atlantic Union Bank |
| $350,000–1 million | INNOVATIVE TECHNOLOGIES INTERNATIONAL, INC | LYNCHBURG, VA | Bank of the James |
| $350,000–1 million | INNOVATIVE WIRELESS TECHNOLOGIES, INC. | LYNCHBURG, VA | Truist Bank |
| $350,000–1 million | INTRAVENE LLC | LYNCHBURG, VA | Bank of the James |
| $150,000–350,000 | IRON & ALE LLC | LYNCHBURG, VA | Select Bank |
| $150,000–350,000 | ISABELLA'S INC | LYNCHBURG, VA | Bank of the James |
| $150,000–350,000 | J.A.W CONSTRUCTION, INC. | LYNCHBURG, VA | Atlantic Union Bank |
| $150,000–350,000 | J.B. MOORE ELECTRICAL INC. | LYNCHBURG, VA | Select Bank |
| $150,000–350,000 | JALISCO, INC. | LYNCHBURG, VA | Select Bank |
| $1–2 million | JAMERSON-LEWIS CONSTRUCTION, INC. | LYNCHBURG, VA | First-Citizens Bank & Trust Company |
| $350,000–1 million | JAMES RIVER DAY SCHOOL INC | LYNCHBURG, VA | Bank of the James |
| $150,000–350,000 | JFC LYNCHBURG MASTER TENANT, LLC | LYNCHBURG, VA | CIBC Bank USA |
| $350,000–1 million | JUSTICE RETAIL OPERATIONS, INC | LYNCHBURG, VA | Bank of the James |
| $150,000–350,000 | JUSTICE TIRE DISTRIBUTORS INC | LYNCHBURG, VA | Bank of the James |
| $350,000–1 million | K & J ENTERPRISES INC | LYNCHBURG, VA | Bank of the James |
| $350,000–1 million | KEY PARTS, INC | LYNCHBURG, VA | Magyar Bank |
| $150,000–350,000 | KUBOTA OF LYNCHBURG LLC | LYNCHBURG, VA | Atlantic Union Bank |
| $350,000–1 million | L&R PRECISION TOOLING INC. | LYNCHBURG, VA | Select Bank |