| $1–2 million | AFS OF MARTINSVILLE, INC. | MARTINSVILLE, VA | First Bank |
| $1–2 million | AMERISTAFF, INC. | MARTINSVILLE, VA | Atlantic Union Bank |
| $1–2 million | APPLIED FELTS, INC. | MARTINSVILLE, VA | Pinnacle Bank |
| $350,000–1 million | BURCH-HODGES-STONE, INC. | MARTINSVILLE, VA | Atlantic Union Bank |
| $150,000–350,000 | CHILDREN'S MEDICAL CENTER LTD | MARTINSVILLE, VA | Atlantic Union Bank |
| $150,000–350,000 | COLLINSVILLE PRINTING CO.,INC. | MARTINSVILLE, VA | Atlantic Union Bank |
| $150,000–350,000 | COMMONWEALTH INSTALLATION LLC | MARTINSVILLE, VA | The Fidelity Bank |
| $150,000–350,000 | COUGAR PAWS INC | MARTINSVILLE, VA | Truist Bank |
| $150,000–350,000 | DR JON'S URGENT CARE CENTER, PC | MARTINSVILLE, VA | Atlantic Union Bank |
| $150,000–350,000 | FAVERO FAMILY PRACTICE INC. | MARTINSVILLE, VA | Atlantic Union Bank |
| $150,000–350,000 | FRIEDRICHS FAMILY EYE CARE CENTER PC | MARTINSVILLE, VA | The Fidelity Bank |
| $150,000–350,000 | GARDNER BARROW & SHARPE PC | MARTINSVILLE, VA | The Fidelity Bank |
| $150,000–350,000 | GARY W SMITH CONTRACTOR INC | MARTINSVILLE, VA | Blue Ridge Bank, National Association |
| $350,000–1 million | GL VIRGINIA MARTINSVILLE, LLC | MARTINSVILLE, VA | Forbright Bank |
| $150,000–350,000 | GRINDSTAFF UNDERGROUND UTILITIES, INC. | MARTINSVILLE, VA | Atlantic Union Bank |
| $150,000–350,000 | HARDIDE COATINGS, INC. | MARTINSVILLE, VA | Atlantic Union Bank |
| $350,000–1 million | KAB, III INC. | MARTINSVILLE, VA | Atlantic Union Bank |
| $350,000–1 million | KOGER AIR CORPORATION | MARTINSVILLE, VA | The Fidelity Bank |
| $350,000–1 million | LIFE STAGES, INC. | MARTINSVILLE, VA | Pinnacle Bank |
| $150,000–350,000 | MARTINSVILLE FMAILY DENTISTRY PC | MARTINSVILLE, VA | United Midwest Savings Bank, National Association |
| $150,000–350,000 | MARTINSVILLE SMILES PLLC | MARTINSVILLE, VA | Truist Bank |
| $150,000–350,000 | MARTINSVILLE URGENT CARE, LLC | MARTINSVILLE, VA | Carter Bank & Trust |
| $150,000–350,000 | NELSON AUTO GROUP SOUTH INC | MARTINSVILLE, VA | Truist Bank |
| $350,000–1 million | NELSON FORD INC. | MARTINSVILLE, VA | Truist Bank |
| $150,000–350,000 | NEW HEIGHTS COMMUNITY SUPPORT, LLC | MARTINSVILLE, VA | Cross River Bank |
| $2–5 million | PIEDMONT REGIONAL COMMUNITY SERVICES BOA | MARTINSVILLE, VA | Carter Bank & Trust |
| $350,000–1 million | PINE PRODUCTS, LLC | MARTINSVILLE, VA | Bank of America, National Association |
| $150,000–350,000 | PRILLAMAN & PACE INC | MARTINSVILLE, VA | Atlantic Union Bank |
| $150,000–350,000 | R & R AUTOMATION | MARTINSVILLE, VA | Truist Bank |
| $350,000–1 million | SECOND CHANCE SUPPORT SERVICES, LLC | MARTINSVILLE, VA | The First Bank and Trust Company |
| $150,000–350,000 | SELLS, HOGG & ASSOCIATES, CPAS, P.C. | MARTINSVILLE, VA | Atlantic Union Bank |
| $150,000–350,000 | SOLID STONE FABRICS, INC. | MARTINSVILLE, VA | Skyline National Bank |
| $150,000–350,000 | SOUTHEASTERN WOOD PRODUCTS, INC. | MARTINSVILLE, VA | Atlantic Union Bank |
| $150,000–350,000 | STONE DYNAMICS INC | MARTINSVILLE, VA | The Fidelity Bank |
| $350,000–1 million | TEXTURING SERVICE LLC | MARTINSVILLE, VA | First American Bank & Trust |
| $150,000–350,000 | THOMAS AGENCY INC | MARTINSVILLE, VA | Atlantic Union Bank |
| $1–2 million | VIRGINIA MIRROR COMPANY INC | MARTINSVILLE, VA | Atlantic Union Bank |
| $350,000–1 million | WARREN TRUCKING COMPANY INCORPORATED | MARTINSVILLE, VA | Blue Ridge Bank, National Association |
| $350,000–1 million | WEST WINDOW CORPORATION | MARTINSVILLE, VA | Atlantic Union Bank |
| $150,000–350,000 | WILL TRANSPORT INC | MARTINSVILLE, VA | Atlantic Union Bank |