| $150,000–350,000 | ACADIANA MEDICINE CLINIC | OPELOUSAS, LA | JPMorgan Chase Bank, National Association |
| $350,000–1 million | AGAPE TOTAL CARE LLC | OPELOUSAS, LA | JD Bank |
| $150,000–350,000 | ARDOIN & KENNEDY LLC | OPELOUSAS, LA | JD Bank |
| $150,000–350,000 | ASPEN CLINIC, INC. | OPELOUSAS, LA | Hancock Whitney Bank |
| $350,000–1 million | BELMATT INC | OPELOUSAS, LA | BankPlus |
| $150,000–350,000 | BIHM CONSTRUCTION COMPANY INC | OPELOUSAS, LA | IBERIABANK |
| $150,000–350,000 | BODEMULLER THE PRINTER INC | OPELOUSAS, LA | American Bank & Trust Company |
| $350,000–1 million | C & G CONTAINERS, INC. | OPELOUSAS, LA | Home Bank, National Association |
| $150,000–350,000 | CAJUN CHEMICALS AND JANITORIAL SUPPLY INC | OPELOUSAS, LA | American Bank & Trust Company |
| $150,000–350,000 | CARE FOR YOU SOCIAL SERVICES LLC | OPELOUSAS, LA | St. Landry Homestead Federal Savings Bank |
| $150,000–350,000 | CHECKERBOARD RESTAURANTS II INC | OPELOUSAS, LA | Gulf Coast Bank |
| $350,000–1 million | COURVELLE HAPPY TOWN USA INC | OPELOUSAS, LA | JPMorgan Chase Bank, National Association |
| $150,000–350,000 | DALE'S FOOD STORE, INC | OPELOUSAS, LA | American Bank & Trust Company |
| $150,000–350,000 | DANNY'S TIRE WORLD INC | OPELOUSAS, LA | American Bank & Trust Company |
| $350,000–1 million | DUPRE CARRIER GODCHAUX AGENCY | OPELOUSAS, LA | American Bank & Trust Company |
| $150,000–350,000 | EEE, L.L.C. | OPELOUSAS, LA | Hancock Whitney Bank |
| $150,000–350,000 | FAMILY CLINIC INC. | OPELOUSAS, LA | JD Bank |
| $150,000–350,000 | FRIED CHICKEN KING INC | OPELOUSAS, LA | St. Landry Homestead Federal Savings Bank |
| $150,000–350,000 | FUSELIER VETERINARY SERVICES LLC | OPELOUSAS, LA | Bank of Sunset & Trust Company |
| $350,000–1 million | GAIENNIE LUMBER COMPANY LLC | OPELOUSAS, LA | Bank of Sunset & Trust Company |
| $150,000–350,000 | GEORGE RAYMOND WILLIAMS MD LLC | OPELOUSAS, LA | Hancock Whitney Bank |
| $150,000–350,000 | GOING SEBASTIEN FISHER AND LEBOUEF LLP | OPELOUSAS, LA | IBERIABANK |
| $150,000–350,000 | GOOD HANDS HOME CARE SERVICE | OPELOUSAS, LA | Celtic Bank Corporation |
| $150,000–350,000 | GUARANTY GLASS INC | OPELOUSAS, LA | American Bank & Trust Company |
| $150,000–350,000 | HOWARD POOL CO. INC | OPELOUSAS, LA | Home Bank, National Association |
| $150,000–350,000 | JIM TATMAN'S MOBILE HOMES INC | OPELOUSAS, LA | M C Bank & Trust Co. |
| $150,000–350,000 | JOHN S DOWLING AND COMPANY | OPELOUSAS, LA | American Bank & Trust Company |
| $350,000–1 million | KEN'S THRIFTY WAY PHARMACY AND HOME MEDICAL, INC. | OPELOUSAS, LA | Hancock Whitney Bank |
| $150,000–350,000 | LILY PAD PEDIATRICS LLC | OPELOUSAS, LA | Bank of Sunset & Trust Company |
| $150,000–350,000 | MORGAN GOUDEAU & ASSOCIATES INC | OPELOUSAS, LA | IBERIABANK |
| $150,000–350,000 | MORROW MORROW RYAN & BASSETT | OPELOUSAS, LA | JD Bank |
| $350,000–1 million | NEW BEGINNINGS ADDICTION RECOVERY CENTER, LLC | OPELOUSAS, LA | Citizens National Bank, National Association |
| $350,000–1 million | OPELOUSAS CATHOLIC SCHOOL INC | OPELOUSAS, LA | Home Bank, National Association |
| $150,000–350,000 | OPELOUSAS FAMILY WORSHIP CENTER INC. | OPELOUSAS, LA | Investar Bank, National Association |
| $150,000–350,000 | OPELOUSAS ORTHOPAEDIC CLINIC INC | OPELOUSAS, LA | JD Bank |
| $350,000–1 million | OUTREACH COMMUNITY DEVELOPMENT CORPORATION, INC. | OPELOUSAS, LA | JD Bank |
| $150,000–350,000 | PIGGLY WIGGLY SOUTH OF OPELOUSAS | OPELOUSAS, LA | American Bank & Trust Company |
| $350,000–1 million | PRAIRIE CONTRACTORS LLC | OPELOUSAS, LA | IBERIABANK |
| $2–5 million | PROGRESSIVE TRACTOR & IMPLEMENT CO, LLC | OPELOUSAS, LA | Bank of Sunset & Trust Company |
| $350,000–1 million | PROMPT SUCCOR NURSING HOME CORPORATION | OPELOUSAS, LA | JPMorgan Chase Bank, National Association |
| $150,000–350,000 | QUALITY CARE PROVIDERS OF LOUISIANA, LLC | OPELOUSAS, LA | American Bank & Trust Company |
| $350,000–1 million | RIGID CONSTRUCTORS LLC | OPELOUSAS, LA | Bank of Erath |
| $150,000–350,000 | ROY MOTORS, INC. | OPELOUSAS, LA | Home Bank, National Association |
| $150,000–350,000 | SAVANNAH BUTLER | OPELOUSAS, LA | Kabbage, Inc. |
| $350,000–1 million | SAVOIE'S SAUSAGE AND FOOD PRODUCT | OPELOUSAS, LA | IBERIABANK |
| $150,000–350,000 | SOPRANO'S SUPERMARKET LLC | OPELOUSAS, LA | IBERIABANK |
| $350,000–1 million | SOUTHWEST LA PRIMARY HEALTHCARE CENTER INC | OPELOUSAS, LA | Hancock Whitney Bank |
| $350,000–1 million | ST LANDRY EMS LLC | OPELOUSAS, LA | The Cottonport Bank |
| $150,000–350,000 | ST LANDRY LUMBER COMPANY LTD | OPELOUSAS, LA | IBERIABANK |
| $2–5 million | STERLING AUTOMOTIVE GROUP, INC. | OPELOUSAS, LA | Hancock Whitney Bank |
| $350,000–1 million | STERLING FORD LINCOLN, LLC | OPELOUSAS, LA | Hancock Whitney Bank |
| $150,000–350,000 | THE WOUND TREATMENT CENTER | OPELOUSAS, LA | JPMorgan Chase Bank, National Association |
| $150,000–350,000 | THRIFTY PHARMACY OF LA OPELOUSAS SOUTH INC | OPELOUSAS, LA | American Bank & Trust Company |
| $1–2 million | TONY CHACHERE'S CREOLE FOOD OF OPELOUSAS, INC. | OPELOUSAS, LA | Gulf Coast Bank |
| $150,000–350,000 | TRIAD ENERGY SERVICES, LLC | OPELOUSAS, LA | The Peoples Bank & Trust Company of Pointe Coupee Parish |
| $150,000–350,000 | VENTRE GUILLORY & WILLIS LLC | OPELOUSAS, LA | American Bank & Trust Company |
| $350,000–1 million | WESTMINSTER CHRISTIAN ACADEMY | OPELOUSAS, LA | Rayne State Bank & Trust Company |